Lung, prostate, breast, ovarian, bladder, oral and skin cancers have been demonstrated to be suppressed by retinoic acid. (9) Another study collected numerous references demonstrating the findings of retinoic acid in protection against melanoma, hepatoma, lung cancer, breast cancer and prostate cancer. However, there’s evidence indicating that the benefits of chemicals like retinoic acid are safest when obtained from food naturally, rather than supplements.
Here we are getting a little bit closer to the roots of disease. It doesn't matter what disease we are talking about, whether we are talking about a common cold or about cardiovascular disease, or cancer or osteoporosis, the root is always going to be at the cellular and molecular level, and more often than not insulin is going to have its hand in it, if not totally controlling it.
If you eat a piece of fruit, for example, you’re not only consuming sugar (in the form of fructose), but also fiber, vitamins, minerals and phytonutrients. All of these things help feed the healthy bacteria in your gut and help your body metabolize the sugar found in the fruit. Instead of craving more and more sugar, you’ll stay satiated for a longer period without the massive blood sugar spikes from consuming a treat with a bunch of refined sugar, she says.
What your dentist told you when you were a kid is true. “Oral bacteria love sugar just like we do, and when they feast on it, acid gets released as a byproduct,” says Dr. Sanda Moldovan, DDS. “This acid attacks the enamel of the teeth and allows bacteria to penetrate into the deeper layer of the tooth structure, called dentin.” The more sugar you eat, the more acidic the mouth becomes and the faster cavities develop. Plus, sugar feeds yeast growth, which might make the corners of your mouth or tongue red. “This also comes with a velcro-like feeling, or sensitivity to spicy foods,” she says. The sugar link is also a reason why diabetes is one of the diseases your teeth can reveal.
To date, studies have confirmed that chronic inflammation contribute to factors that increase your risk of developing cancer, including DNA mutations and cancer cell growth. Research has confirmed that the antioxidants in dark chocolate have a strong ability to fight the DNA damage that could lead to cancer development, as well as reduce certain inflammation enzymes that could encourage its growth (12).
But these benefits could have an even bigger impact: Flavonoids foundin dark chocolate may someday be useful in potentially treating neurodegenerative diseases such as Alzheimer’s. One study in the Journal of Alzheimer’s Disease found an association between eating chocolate and reduced risk of cognitive decline, perhaps due to protective effects of the cocoa flavanols.
Several assays have been used to assess the total antioxidant content of foods, e.g. the 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox) equivalent antioxidant capacity (TEAC) assay , the ferric-reducing ability of plasma (FRAP)  and the oxygen radical absorbance capacity assay (ORAC) assay . Based on careful considerations (see Blomhoff 2005 and Halvorsen et al 2002 for discussion [15,16]) we chose to use a modified version of the FRAP assay by Benzie and Strain  for total antioxidant analysis . Most importantly, the modified FRAP assay is a simple, fast and inexpensive assay with little selectivity. Assay conditions, such as extraction solvents, were optimized regarding detection of both lipophilic and hydrophilic antioxidants . The FRAP assay directly measures antioxidants with a reduction potential below the reduction potential of the Fe3+/Fe2+ couple [16,17]. Thus, the FRAP assay does not measure glutathione. Most other assays have higher reduction potentials and measures glutathione and other thiols . This may be an advantage when using the FRAP assay, because glutathione is found in high concentrations in foods but it is degraded in the intestine and poorly absorbed by humans . A disadvantage of the FRAP assay is its inability to detect other small molecular weight thiols and sulfur containing molecules of e.g. garlic. Most assays for assessing total antioxidant capacity generally result in similar ranking of foods [20-23]. We have now performed a systematic measurement of the total antioxidant content of more than 3100 foods. This novel Antioxidant Food Table enables us to calculate total antioxidant content of complex diets, identify and rank potentially good sources of antioxidants, and provide the research community with comparable data on the relative antioxidant capacity of a wide range of foods.
Herbert had softer stool for all the days of the challenge, and on seven out of the 14 days she went to the bathroom more than once. "This is not normal for me, but everything was 'smoother'. I started using Xylitol [a sweetener] towards the end, but it upset my stomach. This was a side-effect that made it more difficult to sustain the challenge."